Eureka! Institutional Repository

OBJECTIVE:The purpose of this study is to estimate the growth of bacteria in the small intestine in people with diabetes and correlation of their overgrowth by factors such as duration of diabetes and BMI. Recent data suggest the existence of correlation between the intestinal microbiome, obesity and diabetes mellitus type .However, the exact pathogenetic mechanism linking the enteric microbiome with metabolic diseases are not yet fully elucidated. METHOD: To evaluate the existence or not of SIBO, conducted in all study subjects hydrogen breath test (HBT) with administration of glucose solution (50 gr glucose / 250 ml water) as GHBT considered suitable for the detection of SIBO. RESULTS: In the diabetes group in 53.3% (N = 16) of patients were male and in the control group the majority were women (N = 16, 53.3%). The result is that the SIBO in 46.7% (N = 14) of diabetic patients has positive while in the group of non diabetic revealed that only the 26.7% (N = 8), the result was positive. None of the variables of Somatometrics characteristics were not statistically significant. The management of diabetes (Hba1c) and duration not affect significantly a bacterial overgrowth of the small intestine (SIBO). CONCLUSIONS: The presence of type 2 diabetes do not affect the SIBO. None of the variables of somatometric characteristics exhibited statistically significant relationship with the overgrowth of microbes in the small intestine. The management of diabetes (HbA1c) and the duration of diabetes do not affect significantly a bacterial overgrowth of the small intestine (SIBO). To be able to confirm the relationship between type 2 diabetes and SIBO, other studies with more people are needed.