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Introduction: MS is one of the most important neurological diseases due to the high rates of impact in the general population and it’s tendency to affect young people. It is a common disease of unknown cause characterized by multiple demyelinating plaques in the brain and the spinal cord. It is a chronic neurological disease which belongs to the category of the autoimmune diseases. The first symptom appears usually between the age of 20 and 50, rarely before 12 or after 50. Also, it affects more often women than men in a ratio about 2:1 and mostly the white race. Objective: The objective of this paper is to give valuable information to the patients and to the caregivers so they can comprehend the nature of the disease and the changes that inflicts to the body and the psyche. That will make it easier to prepare and cope in the best possible way. Material and Methods: The material which is used is collected from the international bibliography of the last decade, from electronic databases, scientific articles of the Greek and foreign bibliography and from official scientific sites and organizations. Conclusions: MS affects society in a large scale since the target groups of the disease are young people in the most productive period of their lives. The scientific community which research MS has made great steps from 1838 and slowly but steadily decipher the mechanisms of the disease thereby reducing the factors that trigger MS. Yet, till the cure is found, the nurses’ role is not only to comfort the symptoms but to build a relationship with the patient based in trust and to guide him through the correct treatment.