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The scope of this thesis is to study and to present the various models of development web applications usind the ASP.NET platform.Specifically, will study models as Web Forms, Web Pages/Razor and Single Page Apps.Furthermore, will present methodically the tools which are available for the development of applications with these models. Finally, will be a comparative assessment of the models. In more detail, at the first chapter will be an introduction to web applications, to their differences from desktop applications, to the 3-tier architecture where existed. Moreover, will be studied the server side and client side technologies and the cycle development of a web application. At the next chapter will study some tools which are available for web applications development and the Content Management Systems (CMS). At the third chapter will present the ingredients of ASP.NET, the architecture of ASP.NET, the models of the applications and the design’s authorities that govers the ASP.NET. At our main chapter now, the forth chapter, will peruse with details the models of web applications development using the ASP.NET platform. We will start analyzing the Web Forms and their feautures.After that will continue the research with Master Pages and the ASP.NET Ajax Controls. Below will focuse to the challenges of the Web Forms and the differences between Web Forms and MVC. At chapters 5 and 6 will be a study for Web Pages and for ASP.NET Razor. The main theme at the next chapter are the Single Page Apps and the creation of a small project written in Visual Studio. Closing the chapter 7 will be a comparison between the MVC model an MVVM model. At the last chapter, in chapter 8, will be a qualitative evaluation of the models which are analyzed previously and will be collected any conclusions.