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The purpose of the following thesis is to study the applications of mesotherapy in aesthetics and medicine and to attribute its effectiveness. Mesotherapy is the method used in the deepest layers of the human skin to deal with various aesthetic and medical problems and more specifically for treatment of aging skin, cellulite and local fat deposits, as well as hair loss. It is a method that presents many application techniques and in addition to its nature, the substances used also play a very important role and they also have firming and regenerative properties. More and more patients are turning to mesotherapy because of its speed, painless application, its proven effectiveness, and its almost zero recovery time.