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The present work was prepared in the framework of the study of the Strategic Planning for the tourism development, promotion and marketing of the city of Thessaloniki, which was undertaken by the TourLab research laboratory of the International University of Greece, in collaboration with the Thessaloniki Tourism Organization. The work concerns Medical and Educational Tourism as alternative tourism agencies. More specifically, the aim of the work is to investigate whether medical and educational tourism can make a decisive contribution to the tourism development and promotion of the city. In the context of the elaboration of the strategic planning, a very organized and disciplined effort was made from continuous consultations, with the participation of all the involved bodies, in all the issues that concern the city of Thessaloniki. It was deemed necessary to investigate all the sectors that directly or indirectly influence the direction of the requested, in order to form a comprehensive framework of principles which will in the future be the basis for the development of Thessaloniki as a popular tourist destination with a strong brand name. It was studied whether it is important to expand the activities of medical and educational tourism in the city of Thessaloniki, as it will directly and indirectly affect its entire economic, social, political and cultural course. The method of approaching the issue was the research and analysis of Gap and Vrio, and the main conclusions of the analyzes show that Thessaloniki has a number of significant disadvantages, with high economic implications, of a non-permanent nature, mainly concerning the field of state planning, lack of basic mainly transport, water supply and wastewater management. An important disadvantage is the inability to effectively protect investments, but also the lack of strategic planning. Significant advantages, with significant economic implications, include a strong brand name as a medical tourist destination, good health and service infrastructure, as well as hospitality, significant biodiversity, strong cultural and tourist attractions, and a number of appellation of origin products. , climatic conditions. Finally, the intensification of the high level of research by universities and research centers of the city, as well as the connection with university and research centers of other countries is recorded as an advantage.