Eureka! Institutional Repository

Recent studies have shown that schizophrenia is associated with an increased risk of developing type 2 diabetes and depression appears to have a bidirectional relationship with type 2 diabetes. Some studies support that T2DM, schizophrenia and depression are caused by common etiological factors, while others study the existence of common genetic factors. The purpose of this research is to investigate whether patients with schizophrenia and patients with depression are predisposed to developing type 2 diabetes. The sample consisted of 3 groups of 40 people, aged 20-40 years. The first group consists of patients hospitalized with Schizophrenia (F20) at the University Psychiatric Clinic of the University Psychiatric Clinic of the University Psychiatric Hospital, the second of patients hospitalized in the same clinic with depression (F32) and the third group of volunteers of the same age group without mental illness. GLU, HbA1c, Body Mass Index, Total Cholesterol, HDL,LDL, Triglycerides and TSH of the participants. The limitation of the investigation was that psychiatric patients had not received medication by then. Statistical methods were used to analyze the data of the study, which were carried out with the Statistical Package for Social Sciences (SPSS). In addition, an online literature search was carried out in the PubMed electronic database. It was found that there are statistically significant differences for the variables GLU, HbA1c, BMI, CHOL and LDL between the groups. In addition, there were differences in the same sex between the groups but not overall between men and women. It was observed that the mean value of GLU and HbA1c are higher for the schizophrenia group and close to the values of diagnosis of prediabetes. It is concluded that patients with schizophrenia have higher values in terms of key variables for diabetes diagnosis, however, more extensive research should be done in a larger population group.