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In this thesis will be presented follow-up of all those infants who have been hospitalized in the intensive care unit of neonates. Follow-up can be done either in the hospital or in home visits. Both visits and care of infants is done by a wide range of care and health staff (midwives, neonatologists , pediatricians, etc.) or their cooperation. It may also involve a short period of time (from exit from NCIU to 24 hours later) or long-term (up to the age of 18). Goals of this thesis is the normal outcome of NICU infants, prevention of various pathologies, prognosis of subsequent similar disease progression and response to them. Still, health staff should look at some of the parameters to contribute to these goals. Data and review reports were obtained from international and global web sources in the form of books, articles, and online publications. Taking into account all the data and the information of the thesis, we will help both the parents and the health staff to contribute as well as possible to a more normal course of the newborn. In conclusion, the most collective care and cooperation by health staff helps the infant progressively develop into a healthier adult.