Eureka! Institutional Repository

Commonly the reason of autoimmune diseases is unknown, certainly some gene association has been connected with it. The test for their determination is the detection of antinuclear antibodies (ANA). Collagen diseases are the subject of Rheumatology. Their etiology is usually undetermined, although in many of them there is an inherited disposition. Their feature is immunological disorders. In particular, autoantibodies develop towards the organism itself. These diseases affect more than one system. In general, their clinical semantics are localized in areas of the body with connective tissue. Rheumatic diseases are usually detected in the joints and periarticular tissues. Differential diagnosis between rheumatic diseases requires a very detailed clinical approach by the physician. Laboratory and paraclinar control have a great importance in diagnosis. One of the most useful diagnostic methods is examining synovial fluid by puncture. Laboratory assays include tests such as anti-nuclear antibodies, protein immunoelectrophoresis, and so on. Diagnostic is often considered radiographic testing. Apart from the Rheumatologist, collagen diseases may be related to other specialties such as the Orthopedic, Ophthalmologist, Dermatologist, Pediatrician, Pathologist and others.