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Introduction: Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease and the most common neurodegenerative movement disorder, as it affects the intracerebral dopaminergic cells and is characterized by motor mainly impact It affects mostly people over 60 years, and to the 1 % of the world population. Purpose: The purpose of this work is the study of Parkinson's disease, and the role of nurses and health professionals from the beginning to the end of the course of disease, both for the patient and for the family and caregivers. Material and Methods: The material used is therefore the available world literature of the last decade, and came from online libraries, scientific articles in Greek and foreign-language literature and from official scientific bodies online sites and organizations. Conclusions: Parkinson's disease affects many people worldwide and is also not curable. There is a need for further study of the disease, both for identifying the cause of the occurrence, and to treat.