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The purpose of this paper is to study the phenomenon of Malaria as well as its relation with the climate and the temperature. First I describe in detail the disease and its history and I explain how it evolved through the years of the human history. Furthermore I present the five types of malaria, by describing each one of them and finally, based on previous studies, I claim that the type P-falciparum is the most serious and fatal one for the human life. Next I talk about the life cycle of the parasite, by giving a full description of the disease, its symptoms, the ways of the transmission of the disease and finally by claiming that apart for the mosquitos, climate is another factor that contributes to the appearance of the disease. In the second chapter of this paper I am presenting climate per se and some of its dimensions that are important as well as very crucial for the human life, and I give the example of Greece by describing all the changes that have happened, in terms of climate. In the third chapter of this study I claim that climate changes have consequences for the human life, as it is also shown in previous studies. Moreover I talk about the desease in Greece. I describe how it appeared and how it was eliminated, although I am showing that there were incidents, where malaria was diagnosed, even if it was believed that there could not be any more sick patients and I am presenting prevention measures that help us keep away malaria