Eureka! Institutional Repository

OBJECTIVE: The purpose of this study is to examine if and to what extent glucose levels in the blood of patients who undergo cardio-surgical operation are deregulated with the use of extra-corporeal circulation. Furthermore the study investigates the impact of certain factors on this deregulation. Also there will be a comparison between a group of diabetics and one of non-diabetics in order to investigate if there are differences in regard with glucose deregulation as well as the factors mentioned above. Methods and Materials: We studied 81 patients, aged from 41 to 92. The 54.3% were men and the 45.7% were women. We divided them in two groups: 40 diabetics and 41 non-diabetics and we added according to their medical history, factors such as smoking, arterial hypertension, the kind of operation they incurred (1. Bypass, 2 Aortic Valve Replacement, 3 Mitral Valve Replacement.) the Body Mass Index (BMI), and the time period that patients have had diabetes. Also we took into consideration the HbA1c (only in Diabetics) as well as the pre-operative and post-operative glucose rates of the patients. Results: After the statistic analysis of the total sample, it is evident that only hypertension and mortality are related to the deregulation of glucose levels of patients after the operation. Regarding the comparison between the group of diabetics and the one of non-diabetics, it seems that in diabetic group only hypertension is related to the deregulation of glucose in contrast to non-diabetics where it is apparent that gender increases the deregulation and specifically the male gender. The other factors seem that are not connected to the deregulation of glucose levels. Conclusions: It has become evident that hypertension is the only factor which causes deregulation of glucose levels in diabetics. Furthermore it has also been shown that non-diabetic males are deregulated more than females.