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In a field experiment established in the area of Agios Athanasios, Thessaloniki, during the 2021-2022 cultivating season, the potential effect of soil-integrated residues of the silverleaf nightshade (Solanum elaeagnifolium) on the growth and yield of Triticum durum was evaluated. In particular, in this research, the effect of incorporated residues of silverleaf nightshade on germination capacity, twining rate, root and shoot length, and fresh and dry weight of triticum durum was evaluated. In addition, the effect of incorporated silverleaf nightshade residues on total weight, number of spikes, yield, 1000-grain weight and number of grains/ear of triticum durum was evaluated at harvest stage. The results of this research showed that the incorporation of silverleaf nightshade residues before sowing significantly affected the growth and yield of triticum durum. In particular, at the twining stage the number of triticum durum plants and twins in the experimental plots where residues of 30-34 solanum plants/m2 were incorporated were reduced by 63% and 65.7%, respectively compared to the control. However, at harvest the respective reductions in yield, total dry weight, and number of spikes were 54.3%, 57%, and 47.6%.